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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5J
All Species:
7.88
Human Site:
S404
Identified Species:
19.26
UniProt:
Q15735
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15735
NP_001002837.1
1006
107197
S404
V
T
T
S
S
S
T
S
T
L
S
S
S
P
W
Chimpanzee
Pan troglodytes
A0FI79
644
70203
R113
R
N
G
T
S
P
S
R
G
S
V
Q
S
E
G
Rhesus Macaque
Macaca mulatta
XP_001110784
811
87406
K280
S
M
L
N
K
R
L
K
D
A
L
F
T
D
Q
Dog
Lupus familis
XP_543486
1008
107177
S406
V
T
T
S
P
S
T
S
T
S
S
S
S
W
S
Cat
Felis silvestris
Mouse
Mus musculus
P59644
1003
107585
T405
A
T
T
T
T
S
P
T
S
S
W
S
A
Q
P
Rat
Rattus norvegicus
Q9JMC1
1001
107190
S405
T
A
T
S
P
T
S
S
W
S
A
Q
P
T
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507443
768
84124
N237
M
E
V
L
A
P
F
N
F
V
L
V
S
T
V
Chicken
Gallus gallus
XP_415287
1011
110631
D437
K
A
E
Q
R
K
E
D
F
A
T
I
L
H
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_698057
784
85922
K253
E
V
N
S
M
I
N
K
R
L
K
D
A
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780987
442
50512
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.8
78.9
87.5
N.A.
82.2
83.9
N.A.
56.2
42.2
N.A.
40.8
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
32.3
79.4
91.5
N.A.
86.7
88
N.A.
63.6
55.3
N.A.
51.1
N.A.
N.A.
N.A.
N.A.
29.3
P-Site Identity:
100
13.3
0
73.3
N.A.
26.6
20
N.A.
6.6
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
13.3
73.3
N.A.
60
40
N.A.
33.3
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
0
10
0
0
0
0
20
10
0
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
10
10
0
0
10
0
10
0
% D
% Glu:
10
10
10
0
0
0
10
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
10
0
20
0
0
10
0
0
10
% F
% Gly:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
10
0
0
0
10
10
0
20
0
0
10
0
0
0
0
% K
% Leu:
0
0
10
10
0
0
10
0
0
20
20
0
10
10
0
% L
% Met:
10
10
0
0
10
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
10
10
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
20
10
0
0
0
0
0
10
10
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
20
0
10
10
% Q
% Arg:
10
0
0
0
10
10
0
10
10
0
0
0
0
0
0
% R
% Ser:
10
0
0
40
20
30
20
30
10
40
20
30
40
0
10
% S
% Thr:
10
30
40
20
10
10
20
10
20
0
10
0
10
20
0
% T
% Val:
20
10
10
0
0
0
0
0
0
10
10
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _